袁亚利

（教授 硕导）

E-Mail: y198688@swu.edu.cn

联系地址：重庆市北碚区天生路2号伟德手机版APP|中国有限公司

  1986年9月生，四川资中人，2013年6月毕业于伟德手机版APP|中国有限公司，获理学博士学位；2013-2015年伟德手机版APP农业资源与环境团队博士后；2019-2020年香港理工大学访学。2015-2020年伟德手机版APP副教授，硕士生导师；2020年至今伟德手机版APP教授。

主要从事生物纳米技术及电化学和光致电化员工物传感器研究。主持国家自然科学基金项目，中国博士后科学基金项目（一等资助），重庆市自然科学基金项目，重庆市博士后特别资助项目，中央高校人才团队项目（优青）等多项课题。以第一作者和通讯作者在Chem. Sci., Anal. Chem., Chem. Commum., Biosens. Bioelectron. ACS Appl. Mat. Interfaces, Chem.-Eur. J.等重要学术期刊发表影响因子大于5.0的SCI论文30余篇，个人h-index 29。

2016年至今代表性论文

1.        Kou, Beibei, Chai, Yaqin(*), Yuan, Yali (*), Yuan, Ruo(*), A DNA nanopillar as a scaffold to regulate the ratio and distance of mimic enzymes for an efficient cascade catalytic platform, Chem. Sci., 2021,12, 407-411.

2.        Deng, Hanmei, Chai, Yaqin, Yuan, Ruo, Yuan, Yali(*), In Situ Formation of Multifunctional DNA Nanospheres for a Sensitive and Accurate Dual-Mode Biosensor for Photoelectrochemical and Electrochemical Assay, Anal. Chem. 2020, 92, 8364−8370.

3.        Wang, Ding, Chai, Yaqin, Yuan, Yali(*), Yuan, Ruo(*), Simple and Regulable DNA Dimer Nanodevice to Arrange Cascade Enzymes for Sensitive Electrochemical Biosensing, Anal. Chem. 2020, 92, 14197−14202.

4.        Yuan, Yali, Hu, Tao, Zhong, Xia, Zhu, Minghui, Chai, Ya-Qin, Yuan, Ruo(*), Highly Sensitive Photoelectrochemical Biosensor Based on Quantum Dots Sensitizing Bi₂Te₃ Nanosheets and DNA-Amplifying Strategies, ACS Appl Mater Inter 2020, 12, 22624−22629.

5.        Deng, Hanmei, Zhu, Minghui, Huang, Liaojing, Chai, Yaqin, Liu, Xiaorui, Yuan, Ruo(*), Yuan, Yali(*), Novel D-A-D-Type Supramolecular Aggregates with High Photoelectric Activity for Construction of Ultrasensitive Photoelectrochemical Biosensor, Anal. Chem. 2019, 91:12468−12475.

6.        Deng, Han-Mei, Huang, Liao-Jing, Chai, Ya-Qin, Yuan, Ruo(*), Yuan, Ya-Li(*), Ultrasensitive Photoelectrochemical Detection of Multiple Metal Ions Based on Wavelength-Resolved Dual-Signal Output Triggered by Click Reaction, Anal. Chem. 2019, 91: 2861−2868.

7.        Wang, Ding, Chai, Yaqin, Yuan, Yali(*), Yuan, Ruo(*), Precise Regulation of Enzyme Cascade Catalytic Efficiency with DNA Tetrahedron as Scaffold for Ultrasensitive Electrochemical Detection of DNA, Anal. Chem. 2019, 91:3561−3566.

8.        Kong, Lingqi, Wang, Ding, Chai, Yaqin, Yuan, Yali(*), Yuan, Ruo(*), Electrocatalytic Efficiency Regulation between Target-Induced HRP-Mimicking DNAzyme and GO_x with Low Background for Ultrasensitive Detection of Thrombin, Anal. Chem. 2019, 91:10289−10294.

9.        Huang, Liaojing, Deng, Hanmei, Zhong, Xia, Zhu, Minghui, Chai, Yaqin, Yuan, Ruo(*), Yuan, Yali(*), Wavelength distinguishable signal quenching and enhancing toward photoactive material 3,4,9,10-perylenetetracarboxylic dianhydride for simultaneous assay of dual metal ions, Biosens. Bioelectron. 2019, 145:111702.

10.      Zhu, Minghui, Zhong, Xia, Deng, Hanmei, Huang, Liaojing, Yuan, Ruo(*), Yuan, Yali(*), Dependent signal quenching and enhancing triggered by bipedal DNA walker for ultrasensitive photoelectrochemical biosensor, Biosens. Bioelectron. 2019, 143:111618.

11.      Yuan, Yali, Li, Xue, Chen, An-Yi, Wang, Hai-Jun, Chai, Ya-Qin(*), Yuan, Ruo(*), Highly-efficient luminol immobilization approach and exponential strand displacement reaction based electrochemiluminescent strategy for monitoring microRNA expression in cell, Biosens. Bioelectron. 2019,132:62-67.

12.      Zhu, Minghui, Mu, Xiaomei, Deng, Han-Mei, Zhong, Xia, Yuan, Ruo(*), Yuan, Yali(*), Ultrasensitive photoelectrochemical biosensor for MiRNA-21 assay based on target-catalyzed hairpin assembly coupled with distance-controllable multiple signal amplification, Chem. Commun 2019, 55:9622−9625.

13.      Kou, Beibei, Chai, Yaqin, Yuan, Yali(*), Yuan, Ruo(*), Dynamical Regulation of Enzyme Cascade Amplification by a Regenerated DNA Nanotweezer for Ultrasensitive Electrochemical DNA Detection, Anal. Chem. 2018, 90:10701-10706.

14.      Huang, Liaojing, Zhang, Li, Yang, Liu, Yuan, Ruo (*), Yuan, Yali(*), Manganese Porphyrin Decorated on DNA Networks as Quencher and Mimicking Enzyme for Construction of Ultrasensitive Photoelectrochemistry Aptasensor, Biosens. Bioelectron. 2018,104:21-26.

15.      Wang, Ding, Chai, Yaqin, Yuan, Yali(*), Yuan, Ruo (*), A peptide cleavage-based Ultrasensitive electrochemical biosensor with an ingenious two-stage DNA template for highly efficient DNA exponential amplification, Anal. Chem. 2017, 89:8951-8956.

16.      Kou, Beibei, Chai, Yaqin, Yuan, Yali (*), Yuan, Ruo(*), PtNPs as scaffolds to regulate interenzyme distance for construction of efficient enzyme cascade amplification for ultrasensitive electrochemical detection of MMP‑2, Anal. Chem. 2017, 89:9383-9387.

17.      Xie, Hua, Chai, Yaqin, Yuan, Yali(*),Yuan, Ruo(*), Highly effective molecule converting strategy based on enzyme-free dual recycling amplification for ultrasensitive electrochemical detection of ATP, Chem. Commun. 2017,53:8368-8371.

18.      Kou, Beibei ,Zhang, Ling,Xie, Hua,Wang, Ding,Yuan, Yali(*),Chai, Yaqin,Yuan, Ruo(*), DNA Enzyme-Decorated DNA Nanoladders as Enhancer for Peptide Cleavage-Based Electrochemical Biosensor, ACS Appl Mater Inter 2016,8:22869-22874.

19.      Xie, Hua,Wang, Qin,Chai, Yaqin,Yuan, Yali(*),Yuan, Ruo(*), Enzyme-assisted cycling amplification and DNA-templated in-situ deposition of silver nanoparticles for the sensitive electrochemical detection of Hg²⁺, Biosens. Bioelectron. 2016,86:630-635.

20.      Wang, Qin,Gan, Xianxue,Zang, Ruhua. Chai, Yaqin,Yuan, Yali(*),Yuan, Ruo(*), An amplified electrochemical proximity immunoassay for the total protein of Nosema bombycis based on the catalytic activity of Fe₃O₄ NPs towards methylene blue, Biosens. Bioelectron. 2016,81:382-387.