魏晔

教授、博导、重庆市高等学校青年骨干教师 

邮箱：weiye712@swu.edu.cn

课题组网页：https://www.x-mol.com/groups/wei_ye

个人简介：

2001.9—2005.6     华侨大学，材料科学与工程学院，本科               

2005.9—2010.6     中国科学院福建物质结构研究所，有机化学，博士

导师：苏伟平教授

2010.11—2012.12   新加坡南洋理工大学，博士后

合作导师：Naohiko Yoshikai教授

2013.1—2018.8     陆军军医大学，药学院，教授、引进人才

2018.9—至今      伟德手机版APP，伟德手机版APP，教授

研究方向：

课题组主要从事过渡金属精准催化的有机合成方法学研究及在功能分子核心骨架构筑中的应用。通过发展新反应、新催化剂和新催化模式，实现简单分子到高附加值分子的高效转化。内容主要涉及：化学键的选择性切断与转化、可控的自由基接力环化反应、金属/有机小分子协同催化。

发表文章：

独立工作之后

20. Qing-Peng Liu, Xiaoyu Chen, Ning Yu, Yu-Lin Li, Kui-Cheng He, Wei-Hao Zheng, Yu-Qiang Zhou, Kun Jiang,* Limin Yang,* and Ye Wei*. Relay C–H Functionalization Enables De Novo Synthesis of Pyridines and Pyridones. ACS Catal. 2023, 13, 5795.

19. Yu-Lin Li, Ning Yu, Kui-Cheng He, Yu-Qiang Zhou, Wei-Hao Zheng, Kun Jiang*, and Ye Wei*. Skeletal Transformation of Oxindoles into Quinolinones Enabled by Synergistic Copper/Iminium Catalysis. J. Org. Chem. 2023, 88, 4863.

18. Kun Jiang, Shi-Jun Li, Qing-Peng Liu, Ning Yu, Yu-Lin Li, Yu-Qiang Zhou, Kui-Cheng He, Jing Lin, Ting-Yu Zheng, Jian Lang, Yu Lan,* and Ye Wei*. Iminyl Radical-Triggered Relay Annulation for the Construction of Bridged Aza-Tetracycles Bearing Four Contiguous Stereogenic Centers. Chem. Sci. 2022, 13, 7283.

17. Ting-Yu Zheng, Yu-Qiang Zhou, Ning Yu, Yu-Lin Li, Tao Wei, Lan Peng, Yu Ling*, Kun Jiang*, and Ye Wei*. Deconstructive Insertion of Oximes into Coumarins: Modular Synthesis of Dihydrobenzofuran-Fused Pyridones. Org. Lett. 2022, 24, 2282.

16. Jing Lin, Ting-Yu Zheng, Neng-Quan Fan, Pu Zhang, Kun Jiang,* and Ye Wei*. Pyrrole Synthesis through Cu-Catalyzed Cascade [3 + 2] Spiroannulation/Aromatization of Oximes with Azadienes. Org. Chem. Front. 2021, 8, 3776.

15. Fei Du, Shi-Jun Li, Kun Jiang, Rong Zeng, Xi-Chun Pan,* Yu Lan,* Ying-Chun Chen,* and Ye Wei*. Iron-Catalyzed Radical Relay Enabling Modular Synthesis of Fused Pyridines from Alkyne-Tethered Oximes and Alkenes. Angew. Chem., Int. Ed. 2020, 59, 23755.

14. Wu Liang, Kun Jiang, Fei Du, Jie Yang, Li Shuai, Qin Ouyang,* Ying-Chun Chen,* and Ye Wei*. Iron-Catalyzed, Iminyl Radical-Triggered Cascade 1,5-Hydrogen Atom Transfer/(5+2) or (5+1) Annulation: Oxime as a Five-Atom Assembling Unit. Angew. Chem., Int. Ed. 2020, 59, 19222.

13. Jian Lang and Ye Wei*. Difunctionalization of the Isocyano Group: Atom-Economic ­Synthesis of Pyrimidinediones. Synlett 2019, 30, 252 (Invited Paper).

12. Zhen Yang, Kun Jiang, Ying-Chun Chen*, and Ye Wei*. Copper-Catalyzed Dihydroquinolinone Synthesis from Isocyanides and O‑Benzoyl Hydroxylamines. J. Org. Chem. 2019, 84, 3725.

11. Hong-Wen Liang, Zhen Yang, Kun Jiang, Ying Ye, and Ye Wei*. Atom-Economic Silver-Catalyzed Difunctionalization of the Isocyano Group with Cyclic Oxime: Towards Pyrimidinediones. Angew. Chem., Int. Ed. 2018, 57, 5720 (Highlighted by Chin. J. Org. Chem. and Synlett).

10. Jie Yang, Bo Zhao, Yue Xi, Si Sun, Zhen Yang, Ying Ye, Kun Jiang*, and Ye Wei*. Construction of Benzene Rings by Copper-Catalyzed Cycloaddition Reactions of Oximes and Maleimides: An Access to Fused Phthalimides. Org. Lett. 2018, 20, 1216.

9. Qingjuan Han, Kun Jiang, and Ye Wei, Weiping Su*. Transition-Metal-Free, TsOH-Mediated Direct C-H Allylation of 1,4-Benzoquinone with Allylic Alcohols. Asian. J. Org. Chem. 2018, 7, 1385.

8. Ye Wei, Peng Hu, Min Zhang, and Weiping Su*. Metal-Catalyzed Decarboxylative C–H Functionalization. Chem. Rev. 2017, 117, 8864 (ESI高被引论文).

7. Bo Zhao, Hong-Wen Liang, Jie Yang, Zhen Yang, and Ye Wei*. Copper-Catalyzed Intermolecular Cyclization between Oximes and Alkenes: A Facile Access to Spiropyrrolines. ACS Catal. 2017, 7, 5612.

6. Shu-Tao Mei, Hong-Wen Liang, Bin-Teng, Nan-Jin Wang, Li Shuai, Yi Yuan, Ying-Chun Chen, and Ye Wei*. Spirocyclic Sultam and heterobiaryl Synthesis through Rh-Catalyzed Cross-Dehydrogenative Coupling of N-Sulfonyl Ketimines and Thiophenes or Furan. Org. Lett. 2016, 18, 1088.

5. Hong-Wen Liang, Kung Jiang, Wei Ding, Yi Yuan, Li Shuai, and Ye Wei*, and Ying-Chun Chen. Selective Remote C–H Sulfonylation of Aminoquinolines with Arylsulfonyl Chlorides via Copper Catalysis. Chem. Commun. 2015, 51, 16928.

4. Shu-Tao Mei, Nan-Jin Wang, Qin Ouyang, and Ye Wei*. Rhodium-Catalysed Direct C–H Allylation of N-Sulfonyl Ketimines with Allyl Carbonates. Chem. Commun. 2015, 51, 2980.

3. Hong-Wen Liang, Wei Ding, Kun Jiang, Li Shuai, Yi Yuan, and Ye Wei*, and Ying-Chun Chen. Redox-Neutral Palladium-Catalyzed C–H Functionalization to Form Isoindolinones with Carboxylic Acids or Anhydrides as Readily Available Starting Materials. Org. Lett. 2015, 17, 2764.

2. Shu-Tao Mei, Kun Jiang, Nan-Jin Wang, Li Shuai, Yi Yuan, and Ye Wei*. Rhodium-Catalyzed Direct C–H Vinylation of Arenes To Access Styrenes with Vinyl Acetate as a Vinyl Source. Eur. J. Org. Chem. 2015, 6135.

1. Nan-Jin Wang, Shu-Tao Mei, Li Shuai, Yi Yuan, and Ye Wei*. Aerobic Oxidative C–H Olefination of Cyclic N‑Sulfonyl Ketimines Catalyzed by a Rhodium Catalyst. Org. Lett. 2014, 16, 3040.

博士后和研究生期间

6. Ye Wei and Naohiko Yoshikai*. Modular Pyridine Synthesis from Oximes and Enals through Synergistic Copper/Iminium Catalysis. J. Am. Chem. Soc. 2013, 135, 3756 (ESI高被引论文; Highlighted by Synfacts).

5. Ye Wei, Indubhusan Deb, and Naohiko Yoshikai*. Palladium-Catalyzed Aerobic Oxidative Cyclization of N-Aryl Imines: Indole synthesis from Anilines and Ketones. J. Am. Chem. Soc. 2012, 134, 9098 (ESI高被引论文; Highlighted by Angew. Chem. Int. Ed. and Synfacts).

4. Ye Wei and Naohiko Yoshikai*. Oxidative Cyclization of 2-Arylphenols to Dibenzofurans under Pd(II)/Peroxybenzoate Catalysis. Org. Lett. 2011, 13, 5504.

3. Ye Wei and Weiping Su*. Pd(OAc)₂-Catalyzed Oxidative C-H/C-H Cross-Coupling of Electron-Deficient Polyfluoroarenes with Simple Arenes. J. Am. Chem. Soc. 2010, 132, 16377 (ESI高被引论文).

2. Ye Wei, Huaiqing Zhao, Jian Kan, and Weiping Su*; Maochun Hong. Copper-Catalyzed Direct Alkynylation of Electron-Deficient Polyfluoroarenes with Terminal Alkynes Using O₂ as an Oxidant. J. Am. Chem. Soc. 2010, 132, 2522 (Highlighted by Chin. J. Org. Chem. and Angew. Chem. Int. Ed.).

1. Ye Wei, Jian Kan, Min Wang, and Weiping Su*, Maochun Hong. Palladium-Catalyzed Direct Arylation of Electron-Deficient Polyfluoroarenes with Arylboronic Acids. Org. Lett. 2009, 11, 3346 (Highlighted by Synfacts).

科研课题：

1、国家自然科学基金面上项目，2023.1-2026.12，项目负责人（在研）

2、国家自然科学基金面上项目，2018.1-2021.12，项目负责人（已结题）

3、国家自然科学基金青年项目，2014.1-2016.12，项目负责人（已结题）

4、重庆市教委科学技术研究计划重点项目，2022.9-2025.9，项目负责人（在研）

5、重庆市自然科学基金面上项目，2023.8-2026.7，项目负责人（在研）

6、伟德手机版APP引进人才项目，2018.10-2023.12，项目负责人（在研）

获奖情况：

1. 2019年Thieme Chemistry Journals Award

2. 2018年福建省自然科学一等奖（排名第二）