刘春

博士、副教授

个人简介

刘春，男，1993年3月生于河南信阳，中共党员。研究方向为多功能无机纳米材料和新型生物正交纳米催化剂的设计与生物医学应用。长期从事靶向纳米药物递送、前药激活、生物正交纳米催化剂的构建及其在炎症、肿瘤、细菌感染等疾病中的应用研究。共发表了10余篇 SCI 论文，其中以第一作者（含共同一作）的身份在国际知名学术期刊 J. Am. Chem. Soc.，iScience，ACS Nano，Chem. Sci.上共发表了4篇研究论文。

教育和工作经历

2023.03 至今     伟德手机版APP|中国有限公司                               副教授

2017.09-2022.12   中国科学技术大学应用化学与工程学院（长春应化所）   博士

2013.09-2017.06   湘潭大学化学学院                                   学士

联系方式

邮箱：lc0308@swu.edu.cn

地址：重庆市北碚区天生路2号伟德手机版APP|中国有限公司

研究方向

1.       生物正交纳米催化剂的设计与应用

2.       多功能无机纳米材料的合成与修饰、靶向纳米药物递送

代表性论文、专著和专利

1.    Liu, C.; Niu, J.; Cui, T.; Ren, J.; Qu, X., A Motor-Based Carbonaceous Nanocalabash Catalyst for Deep-Layered Bioorthogonal Chemistry. J Am Chem Soc 2022, 144 (42), 19611-19618.

2.    Liu, C.; Du, Z.; Ma, M.; Sun, Y.; Ren, J.; Qu, X., Carbon Monoxide Controllable Targeted Gas Therapy for Synergistic Anti-inflammation. iScience 2020, 23 (9), 101483.

3.    Zhang, W.^#; Liu, C. ^#; Liu, Z.; Zhao, C.; Zhu, J.; Ren, J.; Qu, X., A Cell Selective Fluoride-Activated MOF Biomimetic Platform for Prodrug Synthesis and Enhanced Synergistic Cancer Therapy. ACS Nano 2022, 16 (12), 20975-20984.

4.    Du, Z. ^#; Liu, C. ^#; Liu, Z.; Song, H.; Scott, P.; Du, X.; Ren, J.; Qu, X., In vivo visualization of enantioselective targeting of amyloid and improvement of cognitive function by clickable chiral metallohelices. Chem Sci 2023, 14 (3), 506-513.

5.    Du, Z.; Liu, C.; Song, H.; Scott, P.; Liu, Z.; Ren, J.; Qu, X., Neutrophil-Membrane-Directed Bioorthogonal Synthesis of Inflammation-Targeting Chiral Drugs. Chem 2020, 6 (8), 2060-2072.

6.    Yu, D.; Liu, C.; Zhang, H.; Ren, J.; Qu, X., Glycoengineering artificial receptors for microglia to phagocytose Abeta aggregates. Chem Sci 2021, 12 (13), 4963-4969.

7.    Niu, J.; Zhao, C.*; Liu, C.; Ren, J.; Qu, X., Bio-Inspired Bimetallic Enzyme Mimics as Bio-Orthogonal Catalysts for Enhanced Bacterial Capture and Inhibition. Chem Mater 2021, 33 (20), 8052-8058.

8.    Gao, N.; Liu, Z.; Zhang, H.; Liu, C.; Yu, D.; Ren, J.; Qu, X., Site-Directed Chemical Modification of Amyloid by Polyoxometalates for Inhibition of Protein Misfolding and Aggregation. Angew Chem Int Ed 2022, 61 (16), e202115336.

9.    Zhang, H.; Yu, D.; Liu, S.; Liu, C.; Liu, Z.; Ren, J.; Qu, X., NIR-II Hydrogen-Bonded Organic Frameworks (HOFs) Used for Target-Specific Amyloid-beta Photooxygenation in an Alzheimer's Disease Model. Angew Chem Int Ed 2022, 61 (2), e202109068.

10.   Yu, D.; Zhang, H.; Liu, Z.; Liu, C.; Du, X.; Ren, J.; Qu, X., Hydrogen-Bonded Organic Framework (HOF)-Based Single-Neural Stem Cell Encapsulation and Transplantation to Remodel Impaired Neural Networks. Angew Chem Int Ed 2022, 61 (28), e202201485.